New Mechanical Fat Separation Technique: Adjustable Regenerative Adipose-tissue Transfer (ARAT) and Mechanical Stromal Cell Transfer (MEST)

Mechanical loading of adipose derived stromal cells causes cell alignment

Osteoarthritis is a debilitating disease that affects hundreds of millions of people worldwide. Current research involving growth and characterization of adipose derived stromal cells (ADSC) in vitro offers a potential solution for the treatment of cartilage defects that will allow patients to return to the physical activities they were involved in. Studies have shown that fibroblast cells grow...

Fat and Stromal Vascular Fraction of Adipose Tissue in Reconstructive and Regenerative Surgery: 5 Years Experience

MAteRiAlS AND MethODS: Since 2010, fat grafting was performed in 140 patients. Posttraumatic, postoperative, and postirradiated contour deformities were treated in 74 cases (breast, 31; head and neck, 27; and other localizations, 16). In 61 patients, fat was injected to promote chronic wound healing (venous ulcers, 22; diabetic ulcers, 17; radiation wounds, 16; and other etiology, 6). Adipose-d...

Kiwifruit effect on adipose tissue cell size and cholesteryl ester transfer protein gene expression in high-fat diet fed Golden Syrian hamsters

Objective: The effects of kiwifruit on the histology and cell size of adipose tissue in hyperlipidemic models have not yet been reported. Therefore, this study aimed to investigate the effect of kiwifruit on the adipose tissue cell size and activity as well as the gene expression of cholesteryl ester transfer protein (CETP) in high-fat diet (HFD...

Modeling the Mechanical Behavior of Adipose Tissue

Mechanical homeostasis regulating adipose tissue volume

BACKGROUND The total body adipose tissue volume is regulated by hormonal, nutritional, paracrine, neuronal and genetic control signals, as well as components of cell-cell or cell-matrix interactions. There are no known locally acting homeostatic mechanisms by which growing adipose tissue might adapt its volume. PRESENTATION OF THE HYPOTHESIS Mechanosensitivity has been demonstrated by mesench...